Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• 主要な著者: Takuya Hirata (著者), Yoshihiro Keto (著者), Toshiyuki Funatsu (著者), Shinobu Akuzawa (著者), Masao Sasamata (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2007-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...