Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Ngā kaituhi matua: Takuya Hirata (Author), Yoshihiro Keto (Author), Toshiyuki Funatsu (Author), Shinobu Akuzawa (Author), Masao Sasamata (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2007-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...