Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Main Authors: Takuya Hirata (Author), Yoshihiro Keto (Author), Toshiyuki Funatsu (Author), Shinobu Akuzawa (Author), Masao Sasamata (Author)
• Formato: Livro
• Publicado em: Elsevier, 2007-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...