Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• Автори: Takuya Hirata (Автор), Yoshihiro Keto (Автор), Toshiyuki Funatsu (Автор), Shinobu Akuzawa (Автор), Masao Sasamata (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2007-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...