Unveiling the mechanism of action of acylated temporin L analogues against multidrug-resistant Candida albicans

• Main Authors: Rosa Bellavita (Author), Annarita Falanga (Author), Francesco Merlino (Author), Gabriella D'Auria (Author), Nicola Molfetta (Author), Anella Saviano (Author), Francesco Maione (Author), Umberto Galdiero (Author), Maria Rosaria Catania (Author), Stefania Galdiero (Author), Paolo Grieco (Author), Emanuela Roscetto (Author), Lucia Falcigno (Author), Elisabetta Buommino (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increasing resistance of fungi to conventional antifungal drugs has prompted worldwide the search for new compounds. In this work, we investigated the antifungal properties of acylated Temporin L derivatives, Pent-1B and Dec-1B, against Candida albicans, including the multidrug-resistant strains...