Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe₃O₄ Nanoparticles Drug Delivery System

• Asıl Yazarlar: Aasma Munawwar (Yazar), Amna Sajjad (Yazar), Azhar Rasul (Yazar), Mehran Sattar (Yazar), Farhat Jabeen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug's toxic effects in the traditional chemotherapeutic approach. In this study, we loaded LLY-507, a potent inhibitor of SMYD2, a methyltransferase enzyme, on iron oxide nanoparticles (IONPs). The prepa...