Medical micro- and nanomotors in the body

Attributed to the miniaturized body size and active mobility, micro- and nanomotors (MNMs) have demonstrated tremendous potential for medical applications. However, from bench to bedside, massive efforts are needed to address critical issues, such as cost-effective fabrication, on-demand integration...

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Bibliographic Details
Main Authors: Huaan Li (Author), Fei Peng (Author), Xiaohui Yan (Author), Chun Mao (Author), Xing Ma (Author), Daniela A. Wilson (Author), Qiang He (Author), Yingfeng Tu (Author)
Format: Book
Published: Elsevier, 2023-02-01T00:00:00Z.
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100 1 0 |a Huaan Li  |e author 
700 1 0 |a Fei Peng  |e author 
700 1 0 |a Xiaohui Yan  |e author 
700 1 0 |a Chun Mao  |e author 
700 1 0 |a Xing Ma  |e author 
700 1 0 |a Daniela A. Wilson  |e author 
700 1 0 |a Qiang He  |e author 
700 1 0 |a Yingfeng Tu  |e author 
245 0 0 |a Medical micro- and nanomotors in the body 
260 |b Elsevier,   |c 2023-02-01T00:00:00Z. 
500 |a 2211-3835 
500 |a 10.1016/j.apsb.2022.10.010 
520 |a Attributed to the miniaturized body size and active mobility, micro- and nanomotors (MNMs) have demonstrated tremendous potential for medical applications. However, from bench to bedside, massive efforts are needed to address critical issues, such as cost-effective fabrication, on-demand integration of multiple functions, biocompatibility, biodegradability, controlled propulsion and in vivo navigation. Herein, we summarize the advances of biomedical MNMs reported in the past two decades, with particular emphasis on the design, fabrication, propulsion, navigation, and the abilities of biological barriers penetration, biosensing, diagnosis, minimally invasive surgery and targeted cargo delivery. Future perspectives and challenges are discussed as well. This review can lay the foundation for the future direction of medical MNMs, pushing one step forward on the road to achieving practical theranostics using MNMs. 
546 |a EN 
690 |a Micro- and nanomotors 
690 |a Function integration 
690 |a Controlled propulsion 
690 |a In vivo navigation 
690 |a Biomedical applications 
690 |a Minimally invasive microsurgery 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 517-541 (2023) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S221138352200435X 
787 0 |n https://doaj.org/toc/2211-3835 
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