Nuclear Receptors as Targets for Drug Development: Molecular Mechanisms for Regulation of Obesity and Insulin Resistance by Peroxisome Proliferator-Activated Receptor , CREB-Binding Protein, and Adiponectin

• Autores principales: Atsushi Tsuchida (Autor), Toshimasa Yamauchi (Autor), Takashi Kadowaki (Autor)
• Formato: Libro
• Publicado: Elsevier, 2005-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Obesity is defined as increased mass of adipose tissue, conferring a higher risk of cardiovascular and metabolic disorders such as diabetes, hyperlipidemia, and coronary heart disease. To investigate the role of transcriptional factors, which are involved in adipocytes differentiation and adiposity,...