"Off-Label" use of antibiotics in critical patients

In intensive care units, the most prescribed drugs are antibiotics, as result of the high incidence of infections among patients admitted to these units. In medical practice, antibiotic resistance is a phenomenon with dramatic consequences, which has led to the development of new strategies to solve...

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Bibliographic Details
Main Authors: Cristina Mihaela Ghiciuc (Author), Ioan Iustin Loghin (Author), Aurelia Cretu (Author), Andrei Vicovan (Author), Lacramioara Ochiuz (Author), Irina Teodora Cernescu (Author)
Format: Book
Published: Amaltea Medical Publishing House, 2022-06-01T00:00:00Z.
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Summary:In intensive care units, the most prescribed drugs are antibiotics, as result of the high incidence of infections among patients admitted to these units. In medical practice, antibiotic resistance is a phenomenon with dramatic consequences, which has led to the development of new strategies to solve this public health problem, including the use of "off-label" drugs. Classification as an off-label prescription of a drug mainly refers to: unapproved therapeutic indication, formulation, dose (including dose interval), age or unapproved route of administration. The aim of this paper is to present the categories of appropriate "off-label" use of drugs with a detailed description of the principles of use in this regime of antibiotics as mono- or combo-therapy.
Item Description:10.37897/RJPhP.2022.1.2
2066-5563
2069-6671