β-Cells Different Vulnerability to the Parkinsonian Neurotoxins Rotenone, 1-Methyl-4-phenylpyridinium (MPP⁺) and 6-Hydroxydopamine (6-OHDA)

• Main Authors: Marco Carli (Author), Francesca Vaglini (Author), Eleonora Risaliti (Author), Gianluca Citi (Author), Matilde Masini (Author), Shivakumar Kolachalam (Author), Roberto Maggio (Author), Giovanni Umberto Corsini (Author), Michela Novelli (Author), Vincenzo De Tata (Author), Marco Scarselli (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurotoxins such as rotenone, 1-methyl-4-phenylpyridinium (MPP⁺) and 6-hydroxydopamine (6-OHDA) are well known for their high toxicity on dopaminergic neurons and are associated with Parkinson's disease (PD) in murine models and humans. In addition, PD patients often have...