Dihydropyridine-derived calcium channel blocker as a promising anti-hantavirus entry inhibitor

• Main Authors: Bin Wang (Author), Jiawei Pei (Author), Hui Zhang (Author), Jia Li (Author), Yamei Dang (Author), He Liu (Author), Yuan Wang (Author), Liang Zhang (Author), Libin Qi (Author), Yuewu Yang (Author), Linfeng Cheng (Author), Yangchao Dong (Author), Airong Qian (Author), Zhikai Xu (Author), Yingfeng Lei (Author), Fanglin Zhang (Author), Wei Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hantaviruses, the causative agent for two types of hemorrhagic fevers, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), are distributed from Eurasia to America. HFRS and HPS have mortality rates of up to 15% or 45%, respectively. Currently, no certified therapeut...