Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke
Ischemic stroke is the 5th leading cause of death in the United States. Despite significant improvements in reperfusion therapies, stroke patients still suffer from debilitating neurocognitive deficits. This indicates an essential need to develop novel stroke treatment paradigms. Endogenous uptake t...
Saved in:
Main Authors: | Erica I. Williams (Author), Robert D. Betterton (Author), Thomas P. Davis (Author), Patrick T. Ronaldson (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Transport Mechanisms at the Blood-Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs
by: Patrick T. Ronaldson, et al.
Published: (2022) -
Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity
by: Junzhi Yang, et al.
Published: (2018) -
Ischemic Stroke of Brain
Published: (2018) -
High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats
by: Junzhi Yang, et al.
Published: (2022) -
Pattern Recognition Molecules of Lectin Complement Pathway in Ischemic Stroke
by: Tsakanova G, et al.
Published: (2021)