Cover Image

Acute myeloid leukemia with t(4;12)(q12;p13): A morphological dilemma

Cytogenetics has a pivotal role in risk stratification of acute myeloid leukemia (AML). We report a case of AML with a t(4;12)(q12;p13). To the best of our knowledge, there are about 24 cases of t(4;12) reported in AML which are usually misdiagnosed as lymphoproliferative disorders on morphological...

Full description

Saved in:
Bibliographic Details
Main Authors: Umang V Patel (Author), S R Arun (Author), Deepak Kumar Mishra (Author), Mayur Parihar (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cytogenetics has a pivotal role in risk stratification of acute myeloid leukemia (AML). We report a case of AML with a t(4;12)(q12;p13). To the best of our knowledge, there are about 24 cases of t(4;12) reported in AML which are usually misdiagnosed as lymphoproliferative disorders on morphological assessment. This case showed specific clinical, morphological, and immunophenotypic features such as (1) pseudo lymphoid morphology, (2) dysplasia in granulocytic series, (3) an immature immunophenotype with positivity for CD34 and CD117, and (4) poor treatment response.
Item Description:0377-4929
10.4103/0377-4929.191814

Similar Items