Sinus lift tissue engineering using autologous pulp micro-grafts: A case report of bone density evaluation

Background: Although autografts are the standard procedure for bone grafting, the use of bone regeneration by means of dental pulp stem cell is an alternative that opens a new era in this field. Rigenera Protocol is a new technique able to provide the surgeon autologous pulp micro-grafts. Materials...

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Bibliographic Details
Main Authors: Giorgio Brunelli (Author), Alessandro Motroni (Author), Antonio Graziano (Author), Riccardo D'Aquino (Author), Ilaria Zollino (Author), Francesco Carinci (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
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Summary:Background: Although autografts are the standard procedure for bone grafting, the use of bone regeneration by means of dental pulp stem cell is an alternative that opens a new era in this field. Rigenera Protocol is a new technique able to provide the surgeon autologous pulp micro-grafts. Materials and Methods: At the Department of Oral Surgery, Don Orione Hospital, Bergamo, Italy, one patient underwent sinus lift elevation with pulp stem micro-grafts gentle poured onto collagen sponge. A CT scan control was performed after 4 months and DICOM data were processed with medical imaging software which gives the possibility to use a virtual probe to extract the bone density. Pearson's Chi-square test was used to investigate difference in bone density (BD) between native and newly formed bone. Results: BD in newly formed bone is about the double of native bone. Conclusion: This report demonstrated that micro-grafts derived from dental pulp poured onto collagen sponge are a useful method for bone regeneration in atrophic maxilla.
Item Description:0972-124X
10.4103/0972-124X.119284