Angiotensin-(3-4) modulates the overweight- and undernutrition-induced ACE2 downregulation in renal proximal tubule cells: implications for COVID-19?

• Main Authors: Rafael Luzes (Author), Humberto Muzi-Filho (Author), Amaury Pereira-Acácio (Author), Thuany Crisóstomo (Author), Adalberto Vieyra (Author)
• Format: Bog
• Udgivet: Open Exploration Publishing Inc., 2021-04-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Aim: The renal lesions-including severe acute kidney injury-are severe outcomes in severe acute respiratory syndrome coronavirus 2 infections. There are no reports regarding the influence of the nutritional status on the severity and progress of these lesions. Ageing is also an important risk factor...