Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome
Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation. As an approach for modifying and potentially improving the properties of this inhibitor, we explored ribosome binding and inhibi...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-04-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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