Associations between metabolic disorders and Sjögren's disease

Sjögren's disease (SjD) is a systemic autoimmune disorder characterized by dry eyes and mouth caused by chronic inflammation and is often accompanied by various extra-glandular manifestations, including fatigue and diffuse pain. Although the pathogenesis of the disease remains elusive, several...

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Main Authors: Chihiro Iwaya (Author), Junichi Iwata (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Chihiro Iwaya  |e author 
700 1 0 |a Junichi Iwata  |e author 
245 0 0 |a Associations between metabolic disorders and Sjögren's disease 
260 |b Elsevier,   |c 2024-12-01T00:00:00Z. 
500 |a 1882-7616 
500 |a 10.1016/j.jdsr.2024.06.002 
520 |a Sjögren's disease (SjD) is a systemic autoimmune disorder characterized by dry eyes and mouth caused by chronic inflammation and is often accompanied by various extra-glandular manifestations, including fatigue and diffuse pain. Although the pathogenesis of the disease remains elusive, several factors (e.g. environmental, genetic and hormonal factors, abnormal metabolic status) are associated with this condition. Accumulating evidence suggests a potential role of cholesterol metabolism in immune and non-immune modulation in various diseases. In this review, we summarize the current findings on the associations between cholesterol metabolism and SjD. 
546 |a EN 
690 |a Sjögren's disease 
690 |a Cholesterol metabolism 
690 |a Metabolic disorders 
690 |a Autoimmune disorders 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Japanese Dental Science Review, Vol 60, Iss , Pp 232-238 (2024) 
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856 4 1 |u https://doaj.org/article/3bccb4d6feb94b66bda3fe02685794e1  |z Connect to this object online.