Erucic acid from Isatis indigotica Fort. suppresses influenza A virus replication and inflammation in vitro and in vivo through modulation of NF-κB and p38 MAPK pathway

• Main Authors: Xiaoli Liang (Author), Yuan Huang (Author), Xiping Pan (Author), Yanbing Hao (Author), Xiaowei Chen (Author), Haiming Jiang (Author), Jing Li (Author), Beixian Zhou (Author), Zifeng Yang (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Isatis indigotica Fort. (Ban-Lan-Gen) is an herbal medicine prescribed for influenza treatment. However, its active components and mode of action remain mostly unknown. In the present study, erucic acid was isolated from Isatis indigotica Fort., and subsequently its underlying mechanism against infl...