Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market. To assess the mutagenic and carcinogenic potential of different N-...
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Main Authors: | Andreas H. Göller (Author), Sandra Johanssen (Author), Adam Zalewski (Author), Verena Ziegler (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2024-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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