Omslagsbillede

Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions

The design, synthesis, and evaluation of novel non-steroidal anti-inflammatory drugs (NSAIDs) with better activity and lower side effects are big challenges today. In this work, two 5-acetamido-2-hydroxy benzoic acid derivatives were proposed, increasing the alkyl position (methyl) in an acetamide m...

Fuld beskrivelse

Saved in:

Bibliografiske detaljer
Main Authors:	Cleydson B. R. Santos (Author), Cleison C. Lobato (Author), Sirlene S. B. Ota (Author), Rai C. Silva (Author), Renata C. V. S. Bittencourt (Author), Jofre J. S. Freitas (Author), Elenilze F. B. Ferreira (Author), Marília B. Ferreira (Author), Renata C. Silva (Author), Anderson B. De Lima (Author), Joaquín M. Campos (Author), Rosivaldo S. Borges (Author), José A. H. M. Bittencourt (Author)
Format:	Bog
Udgivet:	MDPI AG, 2023-11-01T00:00:00Z.
Fag:	article
Online adgang:	Connect to this object online.
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Lignende værker

Synthesis and antidiabetic activity of β-acetamido ketones
af: Xing-hua Zhang, et al.
Udgivet: (2011)

CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells
af: Sven Kappel, et al.
Udgivet: (2024)

Validated HPLC method for identification and quantification of p-hydroxy benzoic acid and agnuside in Vitex negundo and Vitex trifolia
af: Sonal Shah, et al.
Udgivet: (2013)

Identification of New Rofecoxib-Based Cyclooxygenase-2 Inhibitors: A Bioinformatics Approach
af: Rozires P. Leão, et al.
Udgivet: (2020)

Rational Approach to New Chemical Entities with Antiproliferative Activity on Ab1 Tyrosine Kinase Encoded by the <i>BCR-ABL</i> Gene: An Hierarchical Biochemoinformatics Analysis
af: Vitor H. da S. Sanches, et al.
Udgivet: (2024)

Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis
af: João P. Pais, et al.
Udgivet: (2022)

Analgesic activity of ocimum sanctum and its combination with tramadol in mice
af: B Tilak, et al.
Udgivet: (2012)

To a Question on the Mechanism of the Antimicrobial Action of Ortho-Benzoic Sulfimide
af: Ekaterina Y. Kasap, et al.
Udgivet: (2020)

Binding Constants of Substituted Benzoic Acids with Bovine Serum Albumin
af: Diliara Khaibrakhmanova, et al.
Udgivet: (2020)

Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos
af: Glauber V. da Costa, et al.
Udgivet: (2019)

Synthesis, physical and chemical properties of esters of 2-((5-(hydroxy(phenyl)methyl)-4-R-1,2,4-triazole-3-yl)thio)ethanoic and 3-(((5-(hydroxy(phenyl)methyl)-4-R-1,2,4-triazole-3-yl)thio)methyl)benzoic acids
af: А. M. Rud, et al.
Udgivet: (2017)

Study on Association of Substituted Benzoic Acids And Other Acids By Physical Methods
af: A. Azzouz, et al.
Udgivet: (2005)

Synthesis, Evaluation of Cytotoxicity and Molecular Docking Studies of the 7-Acetamido Substituted 2-Aryl-5-bromo-3-trifluoroacetylindoles as Potential Inhibitors of Tubulin Polymerization
af: Malose J. Mphahlele, et al.
Udgivet: (2018)

Evaluation of Thermal-Induced Polymorphic Transformation on Desloratadine and Desloratadine-Benzoic Acid Salt
af: Ahmad Ainurofiq, et al.
Udgivet: (2020)

Preparation, characterization and evaluation of aspirin: benzoic acid cocrystals with enhanced pharmaceutical properties
af: Braham Dutt, et al.
Udgivet: (2020)

Carvedilol solubility enhancement by multicomponent crystallization with coformers of benzoic acid, isonicotinamide, and saccharin
af: Iyan Sopyan, et al.
Udgivet: (2023)

Preparation, characterization and evaluation of fenofibrate: benzoic acid cocrystals with enhanced pharmaceutical properties
af: Braham Dutt, et al.
Udgivet: (2021)

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations
af: Vinícius de S. Pinto, et al.
Udgivet: (2019)

Further Analysis on Solubility Measurement and Thermodynamic Modeling of Benzoic Acid in Monosolvents and Binary Mixtures
af: Abolghasem Jouyban, et al.
Udgivet: (2019)

THE ANALGESIC EFFECTS OF AN INNOVATIVE DUMBBELL FLEXOR SYSTEM
af: Hagiu B. A , et al.
Udgivet: (2015)

Analysis of analgesic, antipyretic, and nonsteroidal anti-inflammatory drug use in pediatric prescriptions
af: Tânia R. Ferreira, et al.
Udgivet: (2016)

Analysis of analgesic, antipyretic, and nonsteroidal anti-inflammatory drug use in pediatric prescriptions
af: Tânia R. Ferreira, et al.
Udgivet: (2016)

Analysis of analgesic, antipyretic, and nonsteroidal anti‐inflammatory drug use in pediatric prescriptions
af: Tânia R. Ferreira, et al.
Udgivet: (2016)

New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
af: Rwaida A. Al-Haidari, et al.
Udgivet: (2020)

Pharmacokinetics and Enterohepatic Circulation of 2-(Quinoline-8-carboxamido)benzoic Acid (2-QBA) in Mice
af: Ji-Hyeon Jeon, et al.
Udgivet: (2024)

A Novel Desloratadine-Benzoic Acid Co-Amorphous Solid: Preparation, Characterization, and Stability Evaluation
af: Ahmad Ainurofiq, et al.
Udgivet: (2018)

Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators
af: Siddabasave Gowda B. Gowda, et al.
Udgivet: (2020)

FEATURES OF STORAGE AND TRANSPORTATION OF NARCOTIC ANALGESICS IN CONDITIONS OF EMERGENCY SITUATIONS
af: P. V. Oliynyk, et al.
Udgivet: (2015)

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold
af: Giulia Rotondi, et al.
Udgivet: (2019)

Beta-hydroxy-beta-methyl-butyrate blunts negative age-related changes in body composition, functionality and myofiber dimensions in rats
af: Wilson Jacob M, et al.
Udgivet: (2012)

Use of analgesics in France, following dextropropoxyphene withdrawal
af: E. Van Ganse, et al.
Udgivet: (2018)

Unveiling the Pain Relief Potential: Harnessing Analgesic Peptides from Animal Venoms
af: Ana Flávia Marques Pereira, et al.
Udgivet: (2023)

Bridging the gap: a pragmatic approach to planetary health
af: Rodrigo C. Menezes, et al.
Udgivet: (2024)

Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies
af: Raquel B. M. de Almeida, et al.
Udgivet: (2023)

Analgesic effect of alcoholic Datura stramonium L. seed extract on stereptozotocine-induced diabetic male rats
af: M Khalili Najafabadi, et al.
Udgivet: (2005)

The use of cannabidiol (CBD) as an analgesic component
af: Kristian Kjær-Staal Petersen, et al.
Udgivet: (2023)

Synthesis and characterization of hydroxy crosslinker for polyurethanes
af: Kongkiath Kongsuwan
Udgivet: (2014)

Contribuições da pesquisa para o desenvolvimento profissional docente na perspectiva dos coordenadores dos cursos de licenciatura
af: Ricardo Luiz de Bittencourt, et al.
Udgivet: (2019)

Pharmacological evaluation of processed Cannabis leaves as a non sedative analgesic: The novel approach
af: Swagata Dilip Tavhare, et al.
Udgivet: (2021)

The efficacy of different pre- and post-operative analgesics in the management of pain after orthodontic separator placement: A randomized clinical trial
af: V Sudhakar, et al.
Udgivet: (2014)