Radiolabeling of cidofovir with technetium-99m and biodistribution studies

• Main Authors: Raquel Gregorio Arribada (Author), Nara Caroline Pereira (Author), Valbert Nascimento Cardoso (Author), Armando da Silva Cunha Júnior (Author), André Luís Branco de Barros (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in vitro, showing high radiolabel stability within 24 h. Blood clearance, biodistribution studies, and scintigraphic images were performed in health...