MicroRNA-146a: A Comprehensive Indicator of Inflammation and Oxidative Stress Status Induced in the Brain of Chronic T2DM Rats

• Main Authors: Yangmei Xie (Author), Aiqun Chu (Author), Yonghao Feng (Author), Long Chen (Author), Yiye Shao (Author), Qiong Luo (Author), Xiaolin Deng (Author), Men Wu (Author), Xiaohong Shi (Author), Yinghui Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: It was demonstrated that inflammation and oxidative stress induced by hyperglycemia were closely associated with alteration of miR-146a. Here, we investigated the role of miR-146a in mediating inflammation and oxidative stress in the brain of chronic T2DM rats.Methods: The chronic T2DM (c...