Preparation and Characterisation of Zinc Diethyldithiocarbamate-Cyclodextrin Inclusion Complexes for Potential Lung Cancer Treatment

Zinc diethyldithiocarbamate (Zn (DDC)<sub>2</sub>), a disulfiram metabolite (anti-alcoholism drug), has shown a strong anti-cancer activity in vitro. However, its application was limited by its low aqueous solubility and rapid metabolism. In this study, the solubility enhancement of Zn (...

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Main Authors: Ayşe Kaya (Author), Basel Arafat (Author), Havovi Chichger (Author), Ibrahim Tolaymat (Author), Barbara Pierscionek (Author), Mouhamad Khoder (Author), Mohammad Najlah (Author)
Format: Book
Published: MDPI AG, 2023-12-01T00:00:00Z.
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