Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold

• Main Authors: Giovanna L. Delogu (Author), Antonella Fais (Author), Francesca Pintus (Author), Chinmayi Goyal (Author), Maria J. Matos (Author), Benedetta Era (Author), Amit Kumar (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present work, we use a merger of computational and biochemical techniques as a rational guideline for structural modification of benzofuran derivatives to find pertinent structural features for the butyrylcholinesterase inhibitory activity and selectivity. Previously, we revealed a series of...