Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels

Background: Similarities in the biology of pulmonary hypertension and cancer suggest that anticancer therapies, such as sanguinarine, may also be effective in treating pulmonary hypertension. This, along with underlying biochemical pathways, is investigated in this study.Methods: Rats were subjected...

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Main Authors: Fenling Fan (Author), Yifan Zou (Author), Yousen Wang (Author), Peng Zhang (Author), Xiaoyu Wang (Author), Anthony M. Dart (Author), Yuliang Zou (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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