Design and Development of Levodopa Loaded Polymeric Nanoparticles for Intranasal Delivery

• Main Authors: Mohd Zulhelmy Ahmad (Author), Akmal Hidyat Bin Sabri (Author), Qonita Kurnia Anjani (Author), Juan Domínguez-Robles (Author), Normala Abdul Latip (Author), Khuriah Abdul Hamid (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-03-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Intranasal delivery is an alternative administration route to deliver levodopa (L-Dopa) to the brain. This drug delivery route offers high drug permeability across the nasal epithelium and rapid absorption into the central nervous system (CNS) while bypassing first-pass metabolism. In this study, we...