Vaccine-associated Rubella - a report of two cases and a review of the literature
We report the clinical characteristics of two adult patients, presenting with a typical erythematous rash consistent with rubella disease after MMR vaccination. Both patients had an uncomplicated clinical course and recovered uneventfully. One patient was confirmed to have vaccine-associated rubella...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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| 001 | doaj_3db4dbf3534b4db8a440d422d145f7f0 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Sean Wei Xiang Ong |e author |
| 700 | 1 | 0 | |a Shawn Vasoo |e author |
| 700 | 1 | 0 | |a Sapna P. Sadarangani |e author |
| 700 | 1 | 0 | |a Lin Cui |e author |
| 700 | 1 | 0 | |a Kalisvar Marimuthu |e author |
| 700 | 1 | 0 | |a Poh Lian Lim |e author |
| 700 | 1 | 0 | |a Jing Wen Kong |e author |
| 700 | 1 | 0 | |a Judith Chui Ching Wong |e author |
| 700 | 1 | 0 | |a Kim Yoong Puong |e author |
| 700 | 1 | 0 | |a Kwai Peng Chan |e author |
| 245 | 0 | 0 | |a Vaccine-associated Rubella - a report of two cases and a review of the literature |
| 260 | |b Taylor & Francis Group, |c 2021-01-01T00:00:00Z. | ||
| 500 | |a 2164-5515 | ||
| 500 | |a 2164-554X | ||
| 500 | |a 10.1080/21645515.2020.1765623 | ||
| 520 | |a We report the clinical characteristics of two adult patients, presenting with a typical erythematous rash consistent with rubella disease after MMR vaccination. Both patients had an uncomplicated clinical course and recovered uneventfully. One patient was confirmed to have vaccine-associated rubella via sequencing of virus isolated in viral culture. The other patient had a pharyngeal swab positive for rubella virus PCR, with sequencing matching the vaccine strain. There are few reports of clinical disease from rubella vaccine-strains in the literature. Previous authors have reported severe disseminated vaccine-associated rubella in both immunodeficient and immunocompetent patients. Further study is required to ascertain the incidence, risk factors, and clinical characteristics of this condition; as well as investigate the extent of horizontal transmission to guide infection control recommendations. | ||
| 546 | |a EN | ||
| 690 | |a rubella | ||
| 690 | |a vaccine | ||
| 690 | |a genotyping | ||
| 690 | |a vaccine strain | ||
| 690 | |a mmr | ||
| 690 | |a Immunologic diseases. Allergy | ||
| 690 | |a RC581-607 | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 224-227 (2021) | |
| 787 | 0 | |n http://dx.doi.org/10.1080/21645515.2020.1765623 | |
| 787 | 0 | |n https://doaj.org/toc/2164-5515 | |
| 787 | 0 | |n https://doaj.org/toc/2164-554X | |
| 856 | 4 | 1 | |u https://doaj.org/article/3db4dbf3534b4db8a440d422d145f7f0 |z Connect to this object online. |