Reference values for diaphragm electrical activity (Edi) in newborn infants
Abstract Background Neurally adjusted ventilatory assist is an emerging mode of respiratory support that uses the electrical activity of the diaphragm (Edi) to provide synchronised inspiratory pressure support, proportional to an infant's changing inspiratory effort. Data on Edi reference value...
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2022-09-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_3db923ae55dc4a8ab22e328826234c9b | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Varappriyangga Gurumahan |e author |
| 700 | 1 | 0 | |a Sriganesh Thavalingam |e author |
| 700 | 1 | 0 | |a Tim Schindler |e author |
| 700 | 1 | 0 | |a John Smyth |e author |
| 700 | 1 | 0 | |a Kei Lui |e author |
| 700 | 1 | 0 | |a Srinivas Bolisetty |e author |
| 245 | 0 | 0 | |a Reference values for diaphragm electrical activity (Edi) in newborn infants |
| 260 | |b BMC, |c 2022-09-01T00:00:00Z. | ||
| 500 | |a 10.1186/s12887-022-03619-1 | ||
| 500 | |a 1471-2431 | ||
| 520 | |a Abstract Background Neurally adjusted ventilatory assist is an emerging mode of respiratory support that uses the electrical activity of the diaphragm (Edi) to provide synchronised inspiratory pressure support, proportional to an infant's changing inspiratory effort. Data on Edi reference values for neonates are limited. The objective of this study was to establish reference Edi values for preterm and term neonates who are not receiving respiratory support. Methods This was a prospective observational study of newborn infants breathing spontaneously in room air. The Edi waveform was monitored by a specialised naso/orogastric feeding tube with embedded electrodes positioned at the level of the diaphragm. Edi minimums and peaks were recorded continuously for 4 h without changes to routine clinical handling. Results Twenty-four newborn infants (16 preterm [< 37 weeks' gestation]; 8 term) were studied. All infants were breathing comfortably in room air at the time of study. Edi data were successfully captured in all infants. The mean (±SD) Edi minimum was 3.02 (±0.94) μV and the mean Edi peak was 10.13 (±3.50) μV. In preterm infants the mean (±SD) Edi minimum was 3.05 (±0.91) μV and the mean Edi peak was 9.36 (±2.13) μV. In term infants the mean (±SD) Edi minimum was 2.97 (±1.05) μV and the mean Edi peak was 11.66 (±5.14) μV. Conclusion Reference Edi values were established for both preterm and term neonates. These values can be used as a guide when monitoring breathing support and when using diaphragm-triggered modes of respiratory support in newborn infants | ||
| 546 | |a EN | ||
| 690 | |a Intensive care units | ||
| 690 | |a Neonatal | ||
| 690 | |a Non-invasive ventilation | ||
| 690 | |a Diaphragm | ||
| 690 | |a Pediatrics | ||
| 690 | |a RJ1-570 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n BMC Pediatrics, Vol 22, Iss 1, Pp 1-5 (2022) | |
| 787 | 0 | |n https://doi.org/10.1186/s12887-022-03619-1 | |
| 787 | 0 | |n https://doaj.org/toc/1471-2431 | |
| 856 | 4 | 1 | |u https://doaj.org/article/3db923ae55dc4a8ab22e328826234c9b |z Connect to this object online. |