Killer-Cell Inhibitory Receptors, CD158a/b, are Upregulated by Interleukin-2, but not Interferon-γ or Interleukin-4

• Main Authors: Toshiaki Kogure (Author), Hiroshi Fujinaga (Author), Atsushi Niizawa (Author), Le Xuan Hai (Author), Yutaka Shimada (Author), Hiroshi Ochiai (Author), Katsutoshi Terasawa (Author)
• Format: Book
• Published: Hindawi Limited, 1999-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although it is now accepted that killer-cell inhibitory receptors (KIRs), which were molecularly cloned in 1995, deliver negative signals to natural killer (NK) cells regarding the recognition of target cells, it is still unclear how the expression of these receptors on lymphocytes is regulated. The...