Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Prif Awduron: Xinghui Han (Awdur), Yuanyuan He (Awdur), Gulan Zeng (Awdur), Yonghong Wang (Awdur), Wen Sun (Awdur), Junchao Liu (Awdur), Yanyan Sun (Awdur), Jian Yu (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2017-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...