Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Κύριοι συγγραφείς: Xinghui Han (Συγγραφέας), Yuanyuan He (Συγγραφέας), Gulan Zeng (Συγγραφέας), Yonghong Wang (Συγγραφέας), Wen Sun (Συγγραφέας), Junchao Liu (Συγγραφέας), Yanyan Sun (Συγγραφέας), Jian Yu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2017-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...