Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

• Главные авторы: Xinghui Han (Автор), Yuanyuan He (Автор), Gulan Zeng (Автор), Yonghong Wang (Автор), Wen Sun (Автор), Junchao Liu (Автор), Yanyan Sun (Автор), Jian Yu (Автор)
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• Опубликовано: BMC, 2017-05-01T00:00:00Z.
• Предметы: article
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Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...