Peripheralized sepiapterin reductase inhibition as a safe analgesic therapy
The development of novel analgesics for chronic pain in the last 2 decades has proven virtually intractable, typically failing due to lack of efficacy and dose-limiting side effects. Identified through unbiased gene expression profiling experiments in rats and confirmed by human genome-wide associat...
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Frontiers Media S.A.,
2023-05-01T00:00:00Z.
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