mRNA vaccine-induced IgG mediates nasal SARS-CoV-2 clearance in mice

• Main Authors: Charlie Fricke (Author), Lorenz Ulrich (Author), Jana Kochmann (Author), Janina Gergen (Author), Kristina Kovacikova (Author), Nicole Roth (Author), Julius Beer (Author), Daniel Schnepf (Author), Thomas C. Mettenleiter (Author), Susanne Rauch (Author), Benjamin Petsch (Author), Donata Hoffmann (Author), Martin Beer (Author), Björn Corleis (Author), Anca Dorhoi (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coronavirus disease 2019 (COVID-19) mRNA vaccines that have contributed to controlling the SARS-CoV-2 pandemic induce specific serum antibodies, which correlate with protection. However, the neutralizing capacity of antibodies for emerging SARS-CoV-2 variants is altered. Suboptimal antibody response...