Visual function scale for identification of infants with low respiratory compliance

Aim: Precise estimation of respiratory function is essential to optimise neonatal respiratory care. However, current clinical scores have not been validated with quantitative measures of respiratory function. The aim of this study was to develop a physiological scoring system to predict low respirat...

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Main Authors: Eimei Harada (Author), Masahiro Kinoshita (Author), Sachiko Iwata (Author), Mamoru Saikusa (Author), Kennosuke Tsuda (Author), Ryota Shindou (Author), Takeshi Sahashi (Author), Shin Kato (Author), Yasumasa Yamada (Author), Shinji Saitoh (Author), Osuke Iwata (Author)
Format: Book
Published: Elsevier, 2019-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Eimei Harada  |e author 
700 1 0 |a Masahiro Kinoshita  |e author 
700 1 0 |a Sachiko Iwata  |e author 
700 1 0 |a Mamoru Saikusa  |e author 
700 1 0 |a Kennosuke Tsuda  |e author 
700 1 0 |a Ryota Shindou  |e author 
700 1 0 |a Takeshi Sahashi  |e author 
700 1 0 |a Shin Kato  |e author 
700 1 0 |a Yasumasa Yamada  |e author 
700 1 0 |a Shinji Saitoh  |e author 
700 1 0 |a Osuke Iwata  |e author 
245 0 0 |a Visual function scale for identification of infants with low respiratory compliance 
260 |b Elsevier,   |c 2019-12-01T00:00:00Z. 
500 |a 1875-9572 
500 |a 10.1016/j.pedneo.2019.02.006 
520 |a Aim: Precise estimation of respiratory function is essential to optimise neonatal respiratory care. However, current clinical scores have not been validated with quantitative measures of respiratory function. The aim of this study was to develop a physiological scoring system to predict low respiratory dynamic compliance of <0.6 ml/cmH2O/kg. Methods: Forty-four newborn infants were studied before (dynamic compliance) and shortly after scheduled extubation (physiological signs). A novel scoring system was developed based on the association between physiological signs and dynamic compliance. Results: The respiratory rate was identified as the primary independent variable for dynamic compliance in the univariate analysis. The prediction score for low dynamic compliance comprised the presence of nasal flaring, see-saw respiration, suprasternal/intercostal retraction, and the respiratory rate ranks (0-3). The area under the receiver-operating characteristics curve of the composite score had discriminatory capability of 0.86 (95% confidence interval: 0.75-0.97) to predict low dynamic compliance with the optimal cut-off value of ≥3 (sensitivity, 0.882; specificity, 0.667). Conclusion: Our novel scoring system might help predict newborn infants with low dynamic compliance, who may require escalation of respiratory support, or transfer to higher level units. Key Words: Lung compliance, Newborn infant, Respiratory failure, Resuscitation 
546 |a EN 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Pediatrics and Neonatology, Vol 60, Iss 6, Pp 611-616 (2019) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1875957218306077 
787 0 |n https://doaj.org/toc/1875-9572 
856 4 1 |u https://doaj.org/article/3e5b81dcb59d4d09a5375b5db215fc93  |z Connect to this object online.