Strategies for clinical dose optimization of T cell-engaging therapies in oncology

• Asıl Yazarlar: Kathryn Ball (Yazar), Simon J Dovedi (Yazar), Pavan Vajjah (Yazar), Alex Phipps (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

ABSTRACTInnovative approaches in the design of T cell-engaging (TCE) molecules are ushering in a new wave of promising immunotherapies for the treatment of cancer. Their mechanism of action, which generates an in trans interaction to create a synthetic immune synapse, leads to complex and interconne...