Atherogenic Diet Accelerates Ectopic Mineralization in a Mouse Model of Pseudoxanthoma Elasticum

• Main Authors: Jing-Yi Zhao (Author), Joshua Kingman (Author), Ida Joely Jacobs (Author), Jouni Uitto (Author), Yi Cao (Author), Qiao-Li Li (Author)
• Format: Book
• Published: Wolters Kluwer Health, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract. Objective:. Pseudoxanthoma elasticum (PXE) is a multisystem heritable disorder caused by mutations in the Abcc6 gene. The disease is characterized by ectopic mineralization of the skin, eyes, and arterial blood vessels. Previous studies have suggested that cardiovascular complications in p...