DNA-PK inhibition by M3814 enhances chemosensitivity in non-small cell lung cancer

A significant proportion of non-small cell lung cancer (NSCLC) patients experience accumulating chemotherapy-related adverse events, motivating the design of chemosensitizating strategies. The main cytotoxic damage induced by chemotherapeutic agents is DNA double-strand breaks (DSB). It is thus conc...

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Bibliographic Details
Main Authors: Manni Wang (Author), Siyuan Chen (Author), Yuquan Wei (Author), Xiawei Wei (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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