Assessment of endothelial function by flow-mediated dilation of the brachial artery in adolescents with a history of preeclampsia or a normotensive pregnancy

• Main Authors: Joana Adalgisa Furtado Magalhães Andrade (Author), Francisco Herlânio Costa Carvalho (Author), Rosa Maria Salani Mota (Author), Guilherme Augusto Magalhães Andrade (Author), Helvécio Neves Feitosa (Author), Flávio Lúcio Pontes Ibiapina (Author), Francisco das Chagas Medeiros (Author)
• Format: Book
• Published: Instituto Materno Infantil de Pernambuco, 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Objectives: to determine the prevalence of endothelial dysfunction and its association with a history of mild and severe preeclampsia in adolescents. Methods: a cross-sectional study was carried out at the MEAC-UFC with 103 primiparous adolescents postpartum. The assessment of endothelial function was performed by way of flow-mediated dilatation of the brachial artery. Variables (age, body mass index, gestational age at delivery, systolic and diastolic blood pressure and flow-mediated dilation) were compared between groups. p<0.05 was considered to be statistically significant. Results: twenty-four (23.3%) patients had preeclampsia (PE): 11 mild and 13 severe. The overall prevalence of endothelial dysfunction was 23.3% (21.5% of patients with normotensive pregnancies and 29.2% of the PE patients: 18.2% of those with mild PE and 38.5% of those with severe PE). The figures were statistically significant for systolic blood pressure, p=0.007. Conclusions: patients with a history of PE have higher systolic blood pressure than patients with a history of normotensive pregnancy, but did not have more endothelial dysfunction.

Item Description

1806-9304
10.1590/S1519-38292014000100008