Anti-Tumoral Effects of a (1<i>H</i>-Pyrrol-1-yl)Methyl-1<i>H</i>-Benzoimidazole Carbamate Ester Derivative on Head and Neck Squamous Carcinoma Cell Lines

• Main Authors: Alice Nicolai (Author), Valentina Noemi Madia (Author), Antonella Messore (Author), Daniela De Vita (Author), Alessandro De Leo (Author), Davide Ialongo (Author), Valeria Tudino (Author), Elisabetta Tortorella (Author), Luigi Scipione (Author), Samanta Taurone (Author), Tiziano Pergolizzi (Author), Marco Artico (Author), Roberto Di Santo (Author), Roberta Costi (Author), Susanna Scarpa (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1<i>H</i>-pyrrol-1-yl)methyl-1<i>H</i>-benzoimidazole carbamate ester derivative, named RDS 60. We evaluated the antineoplastic...