Evaluation of serum immunoglobulin (IgG, IgM, IgA) in oral cancer patients - A case control study

Background: Very few studies have been done to evaluate the level of serum immunoglobulins (IgG, IgM, and IgA) in patients with oral cancer as tumor markers. Aims and Objectives: The aim of this study was to estimate the serum immunoglobulins level (IgG, IgM, and IgA) in oral cancer patients and its...

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Main Authors: Vivek M Tarsariya (Author), Nilesh Raval (Author), Dhaval N Mehta (Author), Mukesh K Asrani (Author), Vijay K Asrani (Author), Kaushik S Barot (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
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100 1 0 |a Vivek M Tarsariya  |e author 
700 1 0 |a Nilesh Raval  |e author 
700 1 0 |a Dhaval N Mehta  |e author 
700 1 0 |a Mukesh K Asrani  |e author 
700 1 0 |a Vijay K Asrani  |e author 
700 1 0 |a Kaushik S Barot  |e author 
245 0 0 |a Evaluation of serum immunoglobulin (IgG, IgM, IgA) in oral cancer patients - A case control study 
260 |b Wolters Kluwer Medknow Publications,   |c 2021-01-01T00:00:00Z. 
500 |a 0972-1363 
500 |a 10.4103/jiaomr.jiaomr_240_20 
520 |a Background: Very few studies have been done to evaluate the level of serum immunoglobulins (IgG, IgM, and IgA) in patients with oral cancer as tumor markers. Aims and Objectives: The aim of this study was to estimate the serum immunoglobulins level (IgG, IgM, and IgA) in oral cancer patients and its comparison with control groups and whether these values can be used to predict the severity of disease or not. Materials and Methods: A total of 30 patients with different clinical stages oral cancer and 30 healthy controls were selected at random and subjected for analysis of serum IgG, IgA, and IgM. Statistical methods used were the mean, standard deviation and t test. Results: Significantly elevated levels of all the immunoglobulins was observed in oral cancer patients when compared with the control group and levels were increasing with clinical stages (P < 0.05). Conclusion: All these immunoglobulins are indicative of tumor burden or transformation of malignancy in higher stage and might be used as prognostic indicators in oral cancer. 
546 |a EN 
690 |a iga 
690 |a igg 
690 |a igm 
690 |a oral cancer 
690 |a serum immunoglobulin 
690 |a tumor marker 
690 |a Dentistry 
690 |a RK1-715 
690 |a Medical physics. Medical radiology. Nuclear medicine 
690 |a R895-920 
655 7 |a article  |2 local 
786 0 |n Journal of Indian Academy of Oral Medicine and Radiology, Vol 33, Iss 2, Pp 189-194 (2021) 
787 0 |n http://www.jiaomr.in/article.asp?issn=0972-1363;year=2021;volume=33;issue=2;spage=189;epage=194;aulast=Tarsariya 
787 0 |n https://doaj.org/toc/0972-1363 
856 4 1 |u https://doaj.org/article/3ebb79b7e9cb4074b512e463025c91e5  |z Connect to this object online.