Rapid sensitive validated UPLCâMS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study

• Egile Nagusiak: Sunil Kumar Dubey (Egilea), R.N. Saha (Egilea), Hemanth Jangala (Egilea), S. Pasha (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2013-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A new ultra-performance liquid chromatographyâelectrospray ionization mass spectrometry (UPLCâMS/ESI) method for simultaneous determination of venlafaxine (VEN) and its metabolite O-desmethylvenlafaxine (ODV) in rat plasma has been developed and validated using Venlafaxine d6 as the internal standar...