Ovarian Thecoma with Meigs Syndrome Mimicking Malignancy in Postmenopausal Women

• Main Authors: Chun-Chieh Chia (Author), Soon-Cen Huang (Author)
• Format: Book
• Published: Elsevier, 2005-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1028-4559; 10.1016/S1028-4559(09)60179-0
• Keywords: exploratory laparotomy; Meigs syndrome; ovarian malignancy; ovarian thecoma; Gynecology and obstetrics; RG1-991
• Source: Taiwanese Journal of Obstetrics & Gynecology, Vol 44, Iss 4, Pp 381-383 (2005)

Objective: To report a case of ovarian benign ovarian tumor with massive ascites, hydrothorax and elevation of tumor marker, mimicking an ovarian malignancy. Case Report: A 52-year-old, para 3, female visited our obstetrics and gynecology clinic due to progressive abdominal fullness of 3 weeks' duration. A huge pelvic tumor with massive ascites and hydrothorax was found by a series of imaging studies, including ultrasonography and computed tomography. In addition, serum CA125 was elevated (1,678 U/mL). An exploratory laparotomy was performed under the suspicion of an ovarian malignancy. A huge right ovarian tumor without adhesive bands or a defined metastatic lesion was noted. The gross picture of the yellowish tumor showed a homogeneous solid component with hemorrhage. A right salpingo-oophorectomy was performed. Frozen section showed uniform and cytologically bland-looking spindle cells arranged in fascicles. The final histopathologic findings showed it to be a benign ovarian thecoma. Conclusion: Meigs syndrome is not uncommon in gynecology. The clinical signs and symptoms, and imaging and laboratory findings may not sufficiently differentiate Meigs syndrome from malignancy. An exploratory laparotomy is essential for the final diagnosis of this syndrome.