Characterization of phloroglucinol derivatives and diterpenes in Euphorbia ebracteolata Hayata by utilizing ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Euphorbia ebracteolata Hayata (E. ebracteolata) is a Chinese herbal medicine used for the treatment of tumor diseases. An ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLCâQâTOF/MS) based chemical profiling approach was established for the rapid separation and...

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Main Authors: Can-Jian Wang (Author), Ying-Qiao Jiang (Author), Dong-Hui Liu (Author), Xiao-Hong Yan (Author), Shuang-Cheng MA (Author)
Format: Book
Published: Elsevier, 2013-08-01T00:00:00Z.
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100 1 0 |a Can-Jian Wang  |e author 
700 1 0 |a Ying-Qiao Jiang  |e author 
700 1 0 |a Dong-Hui Liu  |e author 
700 1 0 |a Xiao-Hong Yan  |e author 
700 1 0 |a Shuang-Cheng MA  |e author 
245 0 0 |a Characterization of phloroglucinol derivatives and diterpenes in Euphorbia ebracteolata Hayata by utilizing ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 
260 |b Elsevier,   |c 2013-08-01T00:00:00Z. 
500 |a 2095-1779 
500 |a 10.1016/j.jpha.2013.01.002 
520 |a Euphorbia ebracteolata Hayata (E. ebracteolata) is a Chinese herbal medicine used for the treatment of tumor diseases. An ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLCâQâTOF/MS) based chemical profiling approach was established for the rapid separation and characterization on phloroglucinol derivatives and diterpenes in E. ebracteolata. Three phloroglucinol derivatives and nine diterpenes were identified by exact mass measurement and were further confirmed by Ms2 data. In addition, the chemical profiles of six compounds were acquired by reference standards. Furthermore, the fragmentation rules of phloroglucinol derivatives and diterpenes of E. ebracteolata were analyzed, and each chromatographic peak was classified. Keywords: Phloroglucinol derivatives, Diterpenes, Euphorbia ebracteolata Hayata, UPLC-Q-TOF/MS 
546 |a EN 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Journal of Pharmaceutical Analysis, Vol 3, Iss 4, Pp 292-297 (2013) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2095177913000063 
787 0 |n https://doaj.org/toc/2095-1779 
856 4 1 |u https://doaj.org/article/3f1edef6b9a040afa7cc43b9a2b35d3e  |z Connect to this object online.