Iron Oxide Nanoparticle-Mediated mRNA Delivery to Hard-to-Transfect Cancer Cells

• Main Authors: Jianxi Huang (Author), Guanyou Lin (Author), Taylor Juenke (Author), Seokhwan Chung (Author), Nicholas Lai (Author), Tianxin Zhang (Author), Tianyi Zhang (Author), Miqin Zhang (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

mRNA-based therapeutics have emerged as a promising strategy for cancer treatment. However, the effective delivery of mRNA into hard-to-transfect cancer cells remains a significant challenge. This study introduces a novel approach that utilizes iron oxide nanoparticles (NPs) synthesized through a la...