Targeting Histone Deacetylases 6 in Dual-Target Therapy of Cancer

• Main Authors: Milan Beljkas (Author), Aleksandra Ilic (Author), Alen Cebzan (Author), Branko Radovic (Author), Nemanja Djokovic (Author), Dusan Ruzic (Author), Katarina Nikolic (Author), Slavica Oljacic (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylases (HDACs) are the major regulators of the balance of acetylation of histone and non-histone proteins. In contrast to other HDAC isoforms, HDAC6 is mainly involved in maintaining the acetylation balance of many non-histone proteins. Therefore, the overexpression of HDAC6 is associa...