Epithelioid angiosarcoma arising in a uterine leiomyoma with associated elevated CA-125: A case report

We describe the case of a 67 year old female with longstanding uterine leiomyomas who presented with fatigue, weight loss, elevated CA-125 and an enlarging mass arising from the posterior uterine fundus. Histologic sections of the mass contained a leiomyoma with interspersed foci of malignant epithe...

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Bibliographic Details
Main Authors: Sarah V. Strickland (Author), Mark R. Kilgore (Author), Elise J. Simons (Author), Mara H. Rendi (Author)
Format: Book
Published: Elsevier, 2017-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Sarah V. Strickland  |e author 
700 1 0 |a Mark R. Kilgore  |e author 
700 1 0 |a Elise J. Simons  |e author 
700 1 0 |a Mara H. Rendi  |e author 
245 0 0 |a Epithelioid angiosarcoma arising in a uterine leiomyoma with associated elevated CA-125: A case report 
260 |b Elsevier,   |c 2017-08-01T00:00:00Z. 
500 |a 2352-5789 
500 |a 10.1016/j.gore.2017.05.001 
520 |a We describe the case of a 67 year old female with longstanding uterine leiomyomas who presented with fatigue, weight loss, elevated CA-125 and an enlarging mass arising from the posterior uterine fundus. Histologic sections of the mass contained a leiomyoma with interspersed foci of malignant epithelioid cells forming anastomosing vascular channels. The neoplastic cells were diffusely positive for CD31 and FLI1, supporting the morphologic impression of epithelioid angiosarcoma. Few cases of epithelioid angiosarcoma arising within a leiomyoma have been described. In this report we discuss this association and describe its relation with elevated CA-125. 
546 |a EN 
690 |a Angiosarcoma 
690 |a Epithelioid 
690 |a Leiomyoma 
690 |a CA-125 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
690 |a Neoplasms. Tumors. Oncology. Including cancer and carcinogens 
690 |a RC254-282 
655 7 |a article  |2 local 
786 0 |n Gynecologic Oncology Reports, Vol 21, Iss C, Pp 1-4 (2017) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2352578917300516 
787 0 |n https://doaj.org/toc/2352-5789 
856 4 1 |u https://doaj.org/article/3fd7575b57bf49e9a6106c0e60a3b026  |z Connect to this object online.