Treatment-Responsive Granulomatous-Lymphocytic Interstitial Lung Disease in a Pediatric Case of Common Variable Immunodeficiency
Granulomatous-Lymphocytic Interstitial Lung disease (GLILD) is a granulomatous and lymphoproliferative condition occurring in ~25% of Common Variable Immunodeficiency (CVID) patients with the highest prevalence in the late teen to young adult years. GLILD was first described in adults and carries a...
Збережено в:
| Автори: | , , , , |
|---|---|
| Формат: | Книга |
| Опубліковано: |
Frontiers Media S.A.,
2019-03-01T00:00:00Z.
|
| Предмети: | |
| Онлайн доступ: | Connect to this object online. |
| Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_3fdbcedf32b44775bfa3224f4ea509f7 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Robert Tillman |e author |
| 700 | 1 | 0 | |a R. Paul Guillerman |e author |
| 700 | 1 | 0 | |a Timothy Trojan |e author |
| 700 | 1 | 0 | |a Manuel Silva-Carmona |e author |
| 700 | 1 | 0 | |a Manuel Silva-Carmona |e author |
| 700 | 1 | 0 | |a Ivan K. Chinn |e author |
| 245 | 0 | 0 | |a Treatment-Responsive Granulomatous-Lymphocytic Interstitial Lung Disease in a Pediatric Case of Common Variable Immunodeficiency |
| 260 | |b Frontiers Media S.A., |c 2019-03-01T00:00:00Z. | ||
| 500 | |a 2296-2360 | ||
| 500 | |a 10.3389/fped.2019.00105 | ||
| 520 | |a Granulomatous-Lymphocytic Interstitial Lung disease (GLILD) is a granulomatous and lymphoproliferative condition occurring in ~25% of Common Variable Immunodeficiency (CVID) patients with the highest prevalence in the late teen to young adult years. GLILD was first described in adults and carries a poor prognosis with survival estimated to be reduced by half. Here we report a pediatric case of CVID-associated GLILD that presented with rapid deterioration over 3 months and responded to adult-based treatment with dual chemotherapeutic agents (rituximab and azathioprine), resulting in complete resolution of clinical findings and near complete resolution of radiologic findings. This case highlights the opportunity to achieve a favorable outcome in GLILD following appropriate diagnosis and therapy. | ||
| 546 | |a EN | ||
| 690 | |a Granulomatous-Lymphocytic Interstitial Lung disease | ||
| 690 | |a Common Variable Immunodeficiency | ||
| 690 | |a chemotherapeutic agents | ||
| 690 | |a pediatrics | ||
| 690 | |a treatment | ||
| 690 | |a Pediatrics | ||
| 690 | |a RJ1-570 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pediatrics, Vol 7 (2019) | |
| 787 | 0 | |n https://www.frontiersin.org/article/10.3389/fped.2019.00105/full | |
| 787 | 0 | |n https://doaj.org/toc/2296-2360 | |
| 856 | 4 | 1 | |u https://doaj.org/article/3fdbcedf32b44775bfa3224f4ea509f7 |z Connect to this object online. |