Inclisiran for the treatment of hypercholesterolaemia
Inclisiran is a synthetic small interfering RNA (siRNA) that inhibits the production of proprotein convertase subtilisin/ kexin 9 (PCSK9) in hepatocytes by silencing the translation of PCSK9 mRNA. The result of this mechanism is a decrease in PCSK9 synthesis resulting in decreased degradation of the...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
BioExcel Publishing Ltd,
2024-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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