A clinical case of infectious mononucleosis combined etiology (EBV + CMV) on the background of aplastic anemia in a teenager

Infectious mononucleosis of various etiologies occupies one of the leading places in the structure of childhood infectious diseases. It is known that after suffering Epstein-Barr infectious mononucleosis of viral or cytomegalovirus etiology, there is a risk of agranulocytosis, and aplastic anemia wi...

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Main Authors: E. B. Pavlova (Author), D. O. Ivanov (Author), V. N. Timchenko (Author), N. V. Pavlova (Author), A. N. Nazarova (Author), G. V. Kondratiev (Author), T. M. Chernova (Author), A. V. Fedorova (Author), A. A. Danilina (Author), O. V. Bulina (Author)
Format: Book
Published: LLC "Diagnostics and Vaccines", 2023-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a E. B. Pavlova  |e author 
700 1 0 |a D. O. Ivanov  |e author 
700 1 0 |a V. N. Timchenko  |e author 
700 1 0 |a N. V. Pavlova  |e author 
700 1 0 |a A. N. Nazarova  |e author 
700 1 0 |a G. V. Kondratiev  |e author 
700 1 0 |a T. M. Chernova  |e author 
700 1 0 |a A. V. Fedorova  |e author 
700 1 0 |a A. A. Danilina  |e author 
700 1 0 |a O. V. Bulina  |e author 
245 0 0 |a A clinical case of infectious mononucleosis combined etiology (EBV + CMV) on the background of aplastic anemia in a teenager 
260 |b LLC "Diagnostics and Vaccines",   |c 2023-06-01T00:00:00Z. 
500 |a 2072-8107 
500 |a 10.22627/2072-8107-2023-22-2-65-68 
520 |a Infectious mononucleosis of various etiologies occupies one of the leading places in the structure of childhood infectious diseases. It is known that after suffering Epstein-Barr infectious mononucleosis of viral or cytomegalovirus etiology, there is a risk of agranulocytosis, and aplastic anemia with pancytopenia may occur. The combination of two viruses in the etiology of infectious mononucleosis is usually accompanied by severe forms of the disease and a high risk of complications. A clinical case of a severe form of infectious mononucleosis of combined etiology against the background of aplastic anemia (AA) in a teenager aged 15 years and 9 months is presented. The high risk of developing septic complications in AA during the height of MI was the basis for the abolition of cyclosporine, the main treatment for aplastic anemia in a patient. The use of complex therapy, including etiotropic agents, transfusions of donor blood components, intravenous immunoglobulins, made it possible to stabilize the patient's condition for infectious mononucleosis and achieve positive dynamics. At the same time, decompensation of the state according to AA against the background of an acute infection required further treatment of the patient in a specialized hematological hospital. 
546 |a RU 
690 |a infectious mononucleosis 
690 |a herpesviruses 
690 |a cytomegalovirus 
690 |a epstein-barr virus 
690 |a aplastic anemia 
690 |a pancytopenia 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Детские инфекции (Москва), Vol 22, Iss 2, Pp 65-68 (2023) 
787 0 |n https://detinf.elpub.ru/jour/article/view/846 
787 0 |n https://doaj.org/toc/2072-8107 
856 4 1 |u https://doaj.org/article/40677c931ff24f7c94e690e9a1b44f9d  |z Connect to this object online.